Some recent achievements from the group appear in the Labex TULIP Newslettet today!
Check out the press release on our recent Elife publication:
(more details in the french version: https://www.labex-tulip.fr/Actualites/Comment-les-champignons-pathogenes-s-adaptent-aux-multiples-especes-qu-ils-infectent)
Also in the list of projects selected for a FR-AIB TULIP interlab grant:
Our project FUSSPOT "Impact of fungal secreted signalling peptides on plant symbioses" receives funding by the federative institute of research (FR AIB) and TULIP. This is a collaborative project initiated by Nicolas Frei-dit-Frey @ LRSV (https://www.lrsv.ups-tlse.fr/?-Themes-de-recherche,80-) aiming at exploring the biological activity of fungal small secreted peptides on plant interactions with Rhizophagus irregularis and Sclerotinia sclerotiorum.
As a part of an international consortium led by the group of Richard Oliver from Uni. Curtin (Austalia), we contributed to the assembly and analysis of the complete genome sequence of our favourite fungus Sclerotinia sclerotiorum. The article is published today in Genome Biology and Evolution:
Sclerotinia is featured in eLife, with a bunch of other fungi!
We report a comparative analysis of natural selection for codon optimization across fungi, revealing that it associates with the range of hosts parasites can infect. The analysis includes parasites that are major threats to human and animal health and to food security worldwide. The full report is available at:
Our review on the use of systems biology to study plant-pathogen interactions is online:
Peyraud R, Dubiella U, Barbacci A, Genin S, Raffaele S, Roby D. Advances on plant-pathogen interactions from molecular toward systems biology perspectives. Plant J. 2016 Nov 21.
20/01/17: The post-doc positions are filled. Thanks for applying
Job offer update! We now have
2 Post-doc and 1 research assistant positions available and fully funded
Post doc positions are available immediately for up to 2 years (until november 2018), the RA position will be available from June 2017.
A major objective in our lab is to decipher the genetic architecture of plant quantitative immunity. We are especially focusing on the diversity of quantitative immunity program in multiple plant genotypes and species, and on the connections between immunity and the response to abiotic stress. We also develop a research program aiming at understanding how the fungal pathogen S. sclerotiorum manipulates plant cells to colonize host tissues, and how its virulence program evolves in the context of plant quantitative immunity.
Our approaches are highly multidisciplinary involving methods ranging from molecular and cell biology, genetics, high throughput phenotyping of plants and microbes, genomics and transcriptomics, systems biology and modeling. We are looking for highly motivated and talented collaborators with expertise in these approaches. Experience in plant pathology or fungal microbiology will be seen as an advantage.
For further information, please contact project leader Dr. Sylvain Raffaele +33 561 285 326, firstname.lastname@example.org
Apply by contacting Sylvain Raffaele directly or via the LIPM application system (https://www6.toulouse.inra.fr/lipm/Opportunites-Formations/Candidater).
Thomas and Sylvain are spending 3 days at the Auberge du Cèdre near Montpellier for the 3rd meeting of the "Resistance Network". This is a national meeting sponsored by INRA on all aspects of plant resistance, with a special emphasis this year on durability and biocontrol. Thomas is presenting his PhD work on the evolution of a tradeoff between quantitative immunity and abiotic stress response.
** Lab member paper**: “A Resource Allocation Trade-Off between Virulence and Proliferation Drives Metabolic Versatility in the Plant Pathogen Ralstonia solanacearum” is published in Plos Pathogens by Remi Peyraud et al. This is a part of Remi’s work while he was a post-doc in Stephane Genin’s lab that he finished up while in our group.
** Lab member paper **: “Clathrin-dependent endocytosis is required for immunity mediated by pattern recognition receptor kinases” is published in PNAS by Malick et al. This was Malick’s main piece of work from his first post-doc at the Sainsbury Lab, Norwich.
Our proposal on the effect of climate change on the tradeoff between growth and immunity in Arabidopsis has been funded by the TULIP Labex! Project leaders are Fabrice Roux (LIPM) and Didier Aldon (LRSV) – This will make use of the new plant phenotyping falicities launched earlier this year on campus.
Thomas and Sylvain are attending the Gordon Research Conference on Cellular & Molecular Fungal Biology in Holderness, near Boston, United States. Sylvain is giving a talk on the work by Remi, Malick and Adelin in the session “Biophysics and mathematical modeling”, and Thomas is presenting a poster on comparative genomic analyses in fungal pathogens, with an emphasis on Sclerotinia.
The article describing genome analysis and genetic transformation of Drechmeria coniospora, a fungal pathogen of nematodes, is online (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006017).
We contributed to the secretome analysis in this project developed by the group of Jonathan Ewbank from the University of Marseille.
The group is attending the 2016 edition of the international meeting of the Tulip Labex (https://www.labex-tulip.fr/Actualites/Inscriptions-Meeting-International). The program includes talks from members of the scientific advisory board Sharon Long (Stanford Univ. USA) and Tom Schoener (UC Davis, USA). Sylvain is presenting Olivier and Malick work on the phylogenomics of Sclerotiniaceae fungi.
Sylvain is attending the European Conference on Fungal Genetics in La Cité des Sciences in Paris. Amazing science and plenty of friends and collaborators to meet!
Our ‘Nine trends’ collective minireview is online (http://journal.frontiersin.org/article/10.3389/fpls.2016.00422/full). We review recent research supporting the importance of nine themes (Plant RLPs, small RNAs, Abscisic acid,…) in the molecular interactions between the broad host range fungi Botrytis cinerea and Sclerotinia sclerotiorum and their host plants.